Failed to connect to ASM instance. The connection is closed: The connection is closed

One client OEM reports the following incidents intermittently from OEM 13c.

Host=racnode1.virtuallab
Target type=Automatic Storage Management
Target name=+ASM1_racnode1.virtuallab
Categories=Availability
Message=Failed to connect to ASM instance. The connection is closed: The connection is closed
Severity=Fatal
Event reported time=20/12/2020 09:19:01AM EST
Target Lifecycle Status=Test
Operating System=LINUX
Platform=X86_64
Associated Incident Id=12345
Associated Incident Status=New
Associated Incident Owner=oracle
Associated Incident Acknowledged By Owner=No
Associated Incident Priority=High
Associated Incident Escalation Level=0
Event Type=Target Availability
Event name=Status
Availability status=Down

Let’s do some investigations, and provide the easy workaround if patches are unavailable to some clients.